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Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
The Advisory Committee on Immunization Practices recommends the dengue vaccine, Dengvaxia, for children 9–16 years old with prior laboratory-confirmed dengue virus infection and living in areas ...
Dengue is spread by several species of female mosquitoes of the Aedes genus, principally Aedes aegypti. [1] Infection can be prevented by mosquito elimination and the prevention of bites. [12] Two types of dengue vaccine have been approved and are commercially available.
In May 2024, TAK-003 became the second dengue vaccine to be prequalified by the World Health Organization (WHO). [47] This live-attenuated vaccine, developed by Takeda is similar to the Dengvaxia vaccine in the fact that it contains a weakened version of the four variants of dengue virus. The difference between the two vaccines is the TAK-003 ...
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Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
Dengue symptoms include a high fever, headache, vomiting, muscle and joint pain that can be so severe the disease has been called breakbone fever, and an itching skin rash.
It is based on a weakened combination of the yellow fever virus and each of the four dengue serotypes. [30] [52] Two studies of a vaccine found it was 60% effective and prevented more than 80 to 90% of severe cases. [53] [54] This is less than wished for by some. [50] There are ongoing programs working on a dengue vaccine to cover all four ...