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Hydroxocobalamin is the natural form of vitamin B 12 and a member of the cobalamin family of compounds. [ 6][ 7] It is found in both raw and cooked beef, together with other cobalamins. [ 8] Hydroxocobalamin, or another form of vitamin B 12, are required for the body to make DNA. [ 7]
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [ 2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [ 3]
Hydroxocobalamin injection is a clear red liquid solution. Treatment should take into account the cause and severity of the condition. [6] Treatment is done by vitamin B 12 supplementation, either by mouth or by injection. [3] Initially in high daily doses, followed by less frequent lower doses, as the condition improves. [3]
Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [ 5] Those affected often have a gradual onset. [ 5] The most common initial symptoms are feeling tired and weak. [ 4]
The structure of vitamin B 12 was the first low-molecular weight natural product determined by x-ray analysis rather than by chemical degradation. Thus, while the structure of this novel type of complex biomolecule was established, its chemistry remained essentially unknown; exploration of this chemistry became one of the tasks of the vitamin's chemical synthesis.
Serum vitamin B12. Serum vitamin B12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin, while only 6–20% is binds to transcobalamin ll. [2] Only transcobalamin ll is "active" and can be used by the body. [1]
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