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Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle. In medicine , it is one of several methods for parenteral administration of medications. Intramuscular injection may be preferred because muscles have larger and more numerous blood vessels than subcutaneous tissue, leading to faster absorption than ...
For many biologics (e.g., monoclonal antibodies), injection site reactions are the most common adverse effect of the drug, and have been reported to have an incidence rate of 0.5–40%. [ 2 ] In trials of subcutaneous administration of oligonucleotides , between 22 and 100% of subjects developed reactions depending on the oligonucleotide.
The gauge of the needle used can range from 25 gauge to 27 gauge, while the length can vary between 1 ⁄ 2-inch to 5 ⁄ 8-inch for injections using a syringe and needle. [ 3 ] : 722 For subcutaneous injections delivered using devices such as injector pens , the needle used may be as thin as 34 gauge (commonly 30–32 gauge), and as short as 3 ...
While the standard needle size for vaccination is 1 inch, it's recommended that women over 200 lbs. and men over 260 lbs. get shots with 1.5-inch needles. (Getty Images) (Nicolae Toma / 500px via ...
Today, pen needles are manufactured at shorter needle lengths than required for typical vial and syringe administration, which decreases the pain associated with injection. [2] They are available in multiple lengths and gauge of needle , including 3.5mm, 4mm, 5mm, and 8mm lengths, and 31 through 34 gauge. [ 8 ]
For example, "standard steel hypodermic, butterfly, spinal, trephine, sternal, and standard bone marrow needles are used." Needles that have a short shaft are preferred and safe. For infants up to 6 to 8 months old, 18-gauge needles are used and for children more than 8 months old, 15- or 16- gauge needles are used. [18]
The needle is directed toward the intended target by a freehand technique. The needle size, length and type should be selected based on the site, depth and patient’s body habitus. 22–24G needles are sufficed for most injections. [1] The risk of clinically significant bleeding is minimal, so coagulation tests are not needed before the procedure.
An injection of Auvi-Q autoinjector. Another design has a shape and size of a smartphone which can be put into a pocket. This design also has a retractable needle and automated voice instructions to assist the users on how to correctly use the autoinjector. The "Auvi-Q" epinephrine autoinjector uses this design. [8]