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  2. Gene therapy - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy

    Most focus on severe genetic disorders, including immunodeficiencies, haemophilia, thalassaemia, and cystic fibrosis. Such single gene disorders are good candidates for somatic cell therapy. The complete correction of a genetic disorder or the replacement of multiple genes is not yet possible. Only a few of the trials are in the advanced stages.

  3. Wolf–Hirschhorn syndrome - Wikipedia

    en.wikipedia.org/wiki/Wolf–Hirschhorn_syndrome

    About 87% of cases represent a de novo deletion, while about 13% are inherited from a parent with a chromosome translocation. [4] In the cases of familial transmission, there is a 2 to 1 excess of maternal transmission. Of the de novo cases, 80% are paternally derived. [citation needed] A more uncommon cause for WHS is the formation of a ring ...

  4. Delitto perfetto - Wikipedia

    en.wikipedia.org/wiki/Delitto_perfetto

    Delitto perfetto (Italian: [deˈlitto perˈfɛtto]) is a genetic technique for in vivo site-directed mutagenesis in yeast. This name is the Italian term for "perfect murder", and it refers to the ability of the technique to create desired genetic changes without leaving any foreign DNA in the genome.

  5. Yeast artificial chromosome - Wikipedia

    en.wikipedia.org/wiki/Yeast_artificial_chromosome

    Yeast artificial chromosomes (YACs) are genetically engineered chromosomes derived from the DNA of the yeast, Saccharomyces cerevisiae, which is then ligated into a bacterial plasmid. By inserting large fragments of DNA, from 100–1000 kb, the inserted sequences can be cloned and physically mapped using a process called chromosome walking .

  6. Epistasis and functional genomics - Wikipedia

    en.wikipedia.org/wiki/Epistasis_and_functional...

    Synthetic genetic arrays (SGA) and diploid based synthetic lethality analysis of microarrays (dSLAM) are two key methods which have been used to identify synthetic sick lethal mutants and characterize negative epistatic relationships. Sequencing of the entire yeast genome has made it possible to generate a library of knock-out mutants for ...

  7. The dangers of LED face masks you should know about - AOL

    www.aol.com/lifestyle/dangers-led-face-masks...

    It’s important to have a treatment plan that is specific to your needs." Palep maintained: "Overall, at-home LED masks use varying lower frequencies which are only questionably effective."

  8. What Is Fat Grafting (& Can It Help with Ozempic Face)? I ...

    www.aol.com/lifestyle/fat-grafting-help-ozempic...

    Over the summer, we took a deep dive into “Ozempic Face,” a phenomenon that occurs when quick, significant weight loss leads to a hollowness mainly found along the eyes, the cheek area and the ...

  9. Wolfram syndrome - Wikipedia

    en.wikipedia.org/wiki/Wolfram_syndrome

    Wolfram syndrome, also called DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness), is a rare autosomal-recessive genetic disorder that causes childhood-onset diabetes mellitus, optic atrophy, and deafness as well as various other possible disorders including neurodegeneration. Symptoms can start to appear as early as ...