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20788 Ensembl ENSG00000198911 ENSMUSG00000022463 UniProt Q12772 Q3U1N2 RefSeq (mRNA) NM_004599 NM_033218 RefSeq (protein) NP_004590 NP_150087 Location (UCSC) Chr 22: 41.83 – 41.91 Mb Chr 15: 82.03 – 82.09 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Sterol regulatory element-binding protein 2 (SREBP-2) also known as sterol regulatory element binding transcription factor 2 ...
Nuclear factor erythroid 2-related factor 2 (NRF2), also known as nuclear factor erythroid-derived 2-like 2, is a transcription factor that in humans is encoded by the NFE2L2 gene. [5] NRF2 is a basic leucine zipper (bZIP) protein that may regulate the expression of antioxidant proteins that protect against oxidative damage triggered by injury ...
Once there, two proteases, S1P Tooltip site-1 protease and S2P Tooltip site-2 protease, sequentially cleave the precursor protein, releasing the mature form of SREBPs into the cytoplasm. The mature form then migrates to the nucleus, where it activates the promoter of genes involved in cholesterol uptake or in cholesterol synthesis. SREBP ...
In a statement, his family said: "Our family is suffering more than anyone can imagine. Drew lit up every room he entered. His smile was infectious.
eIF2 is a heterotrimer of a total molar mass of 126 kDa that is composed of the three sub-units: α (sub-unit 1), β (sub-unit 2), and γ (sub-unit 3). The sequences of all three sub-units are highly conserved (pairwise amino acid identities for each sub-unit range from 47 to 72% when comparing the proteins of Homo sapiens and Saccharomyces cerevisiae).
California gun safety regulations going into effect Jan. 1. In September, California Gov. Gavin Newsom signed a series of laws aimed at strengthening gun safety regulations.Those include requiring ...
Nick Lachey is opening up about past hurts.. Speaking to a contestant on season three of The Ultimatum, released on Netflix on Wednesday, Dec. 4, the host, 51, said he understands the pain of ...
Nuclear transport factor 2 is a protein that in humans is encoded by the NUTF2 gene. [4] [5] [6] Function.
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