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  2. Serum vitamin B12 - Wikipedia

    en.wikipedia.org/wiki/Serum_vitamin_B12

    Serum vitamin B 12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin, while only 6–20% is binds to transcobalamin ll. [2] Only transcobalamin ll is "active" and can be used by the body. [1]

  3. Haptocorrin - Wikipedia

    en.wikipedia.org/wiki/Haptocorrin

    Haptocorrin (HC) also known as transcobalamin-1 (TC-1) or cobalophilin is a transcobalamin protein that in humans is encoded by the TCN1 gene. [3] One essential function of haptocorrin is protection of the acid-sensitive vitamin B 12 while it moves through the stomach.

  4. Transcobalamin - Wikipedia

    en.wikipedia.org/wiki/Transcobalamin

    TC-2 binds cobalamin once it has been taken up by enterocytes of the terminal ileum and the "Intrinsic Factor-Vitamin B12" complex has been degraded. TC-2 is then involved with the transport of Vitamin B12 to the tissues, where it binds to its plasma membrane receptor (TC-2R), a heavily glycosylated protein with a monomeric molecular mass of 62 ...

  5. Vitamin B12 - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12

    For this reason, elevated serum homocysteine over 15 micromol/L and methylmalonic acid (MMA) over 0.271 micromol/L are considered better indicators of B 12 deficiency, rather than relying only on the concentration of B 12 in blood. [2] However, elevated MMA is not conclusive, as it is seen in people with B 12 deficiency, but also in elderly ...

  6. Hyperhomocysteinemia - Wikipedia

    en.wikipedia.org/wiki/Hyperhomocysteinemia

    A blood test can be performed to quantify total homocysteine concentration in the plasma, of which approximately 80% is generally protein-bound. Classification of hyperhomocysteinemia is defined with respect to serum concentration as follows: [citation needed] Moderate: 15–30 nmol/mL (or μmol/L) Intermediate: 30–100 nmol/mL; Severe: > 100 ...

  7. These High-Quality Vitamin B12 Supplements Can Help ... - AOL

    www.aol.com/lifestyle/high-quality-vitamin-b12...

    MyKind Organics Vegan B12 Spray. Made with methylcobalamin and oodles of organic fruit and botanicals, one spray a day tastes like raspberries while delivering 500 micrograms of vitamin B12. Plus ...

  8. Homocysteine - Wikipedia

    en.wikipedia.org/wiki/Homocysteine

    Homocysteine levels typically are higher in men than women, and increase with age. [15] [16] Common levels in Western populations are 10 to 12 μmol/L, and levels of 20 μmol/L are found in populations with low B-vitamin intakes or in the elderly (e.g., Rotterdam, Framingham). [17] [18]

  9. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    Acid–base and blood gases are among the few blood constituents that exhibit substantial difference between arterial and venous values. [6] Still, pH, bicarbonate and base excess show a high level of inter-method reliability between arterial and venous tests, so arterial and venous values are roughly equivalent for these. [44]