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In the mother, a serologic diagnosis of syphilis is made using a nontreponemal test for syphilis such as the Venereal Disease Research Laboratory test or Rapid plasma reagin (RPR) followed by a treponemal test, such as the Treponema pallidum particle agglutination assay (TP-PA) (the sequence of testing may be reversed with a treponemal test ...
Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
Overall, prevention of congenital syphilis with prenatal screening for maternal syphilis is the best treatment. Effective prevention requires routine prenatal screening, rapid treatment of all infected mothers, and partner tracing/treatment. Additionally, improved health education on STIs and safe sexual practices is essential.
Many of the syphilis treatment therapies only lead to bacteriostatic results, unless larger concentrations of penicillin are used for bactericidal effects. [ 65 ] [ 66 ] Penicillin overall is the most recommended antibiotic by the Centers for Disease Control, as it shows the best results with prolonged use.
Hutchinson's teeth is a sign of congenital syphilis. [1] Affected people have teeth that are smaller and more widely spaced than normal and which have notches on their biting surfaces. [2] It is named for Sir Jonathan Hutchinson, a British surgeon and pathologist, who first described it. [3] Hutchinson's teeth form part of Hutchinson's triad. [2]
Newborn syphilis cases, which can be fatal, have risen more than tenfold in the last decade and almost 32% in a single year, according to a report from the Centers for Disease Control and ...
TORCH syndrome is a cluster of symptoms caused by congenital infection with toxoplasmosis, rubella, cytomegalovirus, herpes simplex, and other organisms including syphilis, parvovirus, and Varicella zoster. [1] Zika virus is considered the most recent member of TORCH infections. [2]
Syphilis rates in Texas continue to climb, alarming healthcare workers who see the highest increases among pregnant people and newborns. A shortage of treatment is complicating efforts to combat it.
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