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Diagramatic representation of mucosal erosion (left), excoriation (center), and ulceration (right) Simplistic representation of the life cycle of mouth ulcers. An ulcer (/ ˈ ʌ l s ər /; from Latin ulcus, "ulcer, sore") [2] is a break in the skin or mucous membrane with loss of surface tissue and the disintegration and necrosis of epithelial tissue. [3]
Anti-ulcer agents are medications or supplements used to cure the damage of mucosal layer on organs to prevent the damage from further extending to deeper regions to cause complications. An anti-ulcer medication for treating mouth ulcer is triamcinolone, a corticosteroid. Other anti-ulcer supplements include vitamin B2 and vitamin B12.
Ulcers may act as a site for local infection and a portal of entry for oral flora that, in some instances, may cause septicaemia (especially in immunosuppressed patients). Therefore, oral mucositis can be a dose-limiting condition, disrupting a patient’s optimal cancer treatment plan and consequentially decreasing their chances of survival. [5]
Amlexanox is the active ingredient in a common topical treatment for recurrent aphthous ulcers of the mouth (canker sores), [2] reducing both healing time [3] and pain. [4] Amlexanox 5% paste is well tolerated, [ 5 ] and is typically applied four times per day directly on the ulcers. [ 3 ]
The tumor commonly presents on sun-exposed areas (e.g. back of the hand, scalp, lip, and superior surface of pinna) On the lip, the tumor forms a small ulcer, which fails to heal and bleeds intermittently; Evidence of chronic skin photodamage, as in multiple actinic keratoses (solar keratoses) The tumor grows relatively slowly
Behçet's disease is a triad of mouth ulcers, genital ulcers and anterior uveitis. [8] The main feature of Behçet's disease is aphthous-like ulceration, but this is usually more severe than seen in aphthous stomatitis without a systemic cause, and typically resembles major or herpetiforme ulceration or both.
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Mouth and genital ulcers with inflamed cartilage syndrome or MAGIC syndrome is a condition in which an individual exhibits symptoms of both relapsing polychondritis (RP) and Behcet's disease (BD). [1] Inflammatory ulcers in the mouth, genitalia, and skin are the hallmark of Behcet's disease (BD), a multisystem illness that is chronic and ...
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