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Phenobarbital is one of the first-line drugs of choice to treat epilepsy in dogs, as well as cats. [11] It is also used to treat feline hyperesthesia syndrome in cats when anti-obsessional therapies prove ineffective. [72] It may also be used to treat seizures in horses when benzodiazepine treatment has failed or is contraindicated. [73]
[2] [3] [4] This theory is disputed on account of there being variable responses within affected cats to the antiepileptic drugs used for treatment and a lack of known neurological cause with no evidence having been found to demonstrate intracranial or extracranial causes of epilepsy.
Cats can have reactive, primary or secondary seizures. Idiopathic seizures are not as common in cats as in dogs; however, a 2008 study conducted showed that of 91 feline seizures, 25% were suspected to have had idiopathic epilepsy. [11] In the same group of 91 cats, 50% were secondary seizures and 20% reactive. [11]
Both newer and older drugs are generally equally effective in new onset epilepsy. [42] The newer drugs tend to have fewer side effects. [42] For newly diagnosed partial or mixed seizures, there is evidence for using gabapentin, lamotrigine, oxcarbazepine or topiramate as monotherapy. [42]
praziquantel – treatment of infestations of the tapeworms Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus; prazosin – sympatholytic used in hypertension and abnormal muscle contractions; prednisolone – glucocorticoid (steroid) used in the management of inflammation and auto-immune disease, primarily in cats
Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat neuropathic pain and also for partial seizures [10] [7] of epilepsy. It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. [11]
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