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Diagram showing the site of injection of the product Vasalgel, a vasectomy alternative. Reversible inhibition of sperm under guidance (RISUG), formerly referred to as the synthetic polymer styrene maleic anhydride (SMA), is the development name of a male contraceptive injection developed at IIT Kharagpur in India by the team of Dr. Sujoy K. Guha.
Vasalgel is composed of 25% styrene-alt-maleic acid (SMA acid) dissolved in dimethyl sulfoxide. [9] The major difference between RISUG and Vasalgel is that Vasalgel is composed of SMA acid without SMA anhydride, which allows for a longer shelf-life, smaller probability of hydrolysis to an acid, and less complex production process. [9]
RISUG is an injectable male contraceptive vas-occlusive gel that has been in development in India since the 1970s, [144] [145] and has shown high effectiveness at pregnancy prevention in multiple clinical trials through Phase III in India, [146] [147] [148] though the results of the largest phase III study were published in a questionably peer ...
Male birth control could be on the way. While it hasn't hit human trials yet, the gel contraceptive is being developed to have long lasting effects similar to a vasectomy.The target market date ...
Founded in 2005, Parsemus is an advocate of research into the plausibility of RISUG (and a method based on RISUG, called Vasalgel), a reversible male contraceptive. [2] [3] The foundation began procuring RISUG's United States intellectual property rights in November 2010, completed the acquisition process in February 2012, and is for the past 8 years conducting toxicology tests as an initial ...
Although Vasalgel and RISUG® are based on the same concept of using a polymer gel injected into the vas deferens, the formulations are not the same. And RISUG has been developed and tested in India over multiple decades, while Vasalgel is being developed in the United States to conform to the latest FDA and international codes of production ...
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