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  2. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban bears a striking structural similarity to the antibiotic linezolid: both drugs share the same oxazolidinone-derived core structure. [39] Accordingly, rivaroxaban was studied for any possible antimicrobial effects and for the possibility of mitochondrial toxicity, which is a known complication of long-term linezolid use. [40]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain . [ 2 ]

  4. Is 'healthy candy' actually good for you? Experts discuss ...

    www.aol.com/news/healthy-candy-actually-good...

    The experts agree that the "healthy" labeling on these candy may be misleading and cause people to consume more than they normally would, increasing the risk of short-term side effects. Healthier ...

  5. Andexanet alfa - Wikipedia

    en.wikipedia.org/wiki/Andexanet_alfa

    Common side effects include pneumonia and urinary tract infections. [9] Severe side effects may include blood clots, heart attacks, strokes, or cardiac arrest. [9] It works by binding to rivaroxaban and apixaban. [9] It was approved for medical use in the United States in May 2018. [8] It was developed by Portola Pharmaceuticals. [10]

  6. Can Weight Loss Drugs Make You Boring? Doctors Explain ...

    www.aol.com/lifestyle/weight-loss-drugs-boring...

    Again, this isn't a common side effect. But if you’re experiencing negative mood or personality changes (or any other Ozempic side effects ), talk to your doctor ASAP, say both experts.

  7. Bayer's patent for blood thinner Xarelto invalid, UK court rules

    www.aol.com/news/bayers-patent-blood-thinner...

    Bayer's patent covering its best-selling blood thinner Xarelto is invalid, London's High Court ruled on Friday in a blow to the German drugmaker. The company's blockbuster Xarelto drug generated ...

  8. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.

  9. Many of the antidepressants I was prescribed have a potential side effect of weight gain. In late 2021, I got on the scale and was the same weight that I was when I was nine months pregnant with ...