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The sodium channels linked to taste receptors can be inhibited by amiloride, and the creation of new taste buds and saliva can be impeded by antiproliferative drugs. [13] Saliva can have traces of the drug, giving rise to a metallic flavor in the mouth; examples include lithium carbonate and tetracyclines . [ 13 ]
Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [11] It is used either alone or with other antibiotics to treat pelvic inflammatory disease , endocarditis , and bacterial vaginosis . [ 11 ]
The metronidazole tablet may have an unpleasant metallic taste, deteriorating drug compliance. [47] This medication may also induce rare side effect in the central nervous system, including neurotoxicity ( encephalopathy , peripheral neuropathy , seizure ).
Here are the common causes of a metallic taste in mouth, and how you can get rid of it. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ...
These are located on top of the taste receptor cells that constitute the taste buds. The taste receptor cells send information detected by clusters of various receptors and ion channels to the gustatory areas of the brain via the seventh, ninth and tenth cranial nerves. On average, the human tongue has 2,000–8,000 taste buds. [2]
The diagram above depicts the signal transduction pathway of the sweet taste. Object A is a taste bud, object B is one taste cell of the taste bud, and object C is the neuron attached to the taste cell. I. Part I shows the reception of a molecule. 1. Sugar, the first messenger, binds to a protein receptor on the cell membrane. II.
Antibiotics such as metronidazole, tinidazole, cephamandole, latamoxef, cefoperazone, cefmenoxime, and furazolidone, cause a disulfiram-like chemical reaction with alcohol by inhibiting its breakdown by acetaldehyde dehydrogenase, which may result in vomiting, nausea, and shortness of breath. [62]
Dysgeusia – altered taste sensation (e.g., a metallic taste) [1] and dysosmia, altered sense of smell. [3] Intraoral halitosis [1] – possibly due to increased activity of halitogenic biofilm on the posterior dorsal tongue (although dysgeusia may cause a complaint of nongenuine halitosis in the absence of hyposalivation).