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Bst1 (Bone marrow stromal cell antigen 1, ADP-ribosyl cyclase 2, CD157) is an enzyme that in humans is encoded by the BST1 gene. [ 5 ] [ 6 ] [ 7 ] CD157 is a paralog of CD38 , both of which are located on chromosome 4 (4p15) in humans.
Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. [2] In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). [3] It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells.
Bone marrow was the original source of MSCs, [16] and is still the most frequently utilized source. These bone marrow stem cells do not contribute to the formation of blood cells, and so do not express the hematopoietic stem cell marker CD34. They are sometimes referred to as bone marrow stromal stem cells. [17]
The cells which make up stroma tissues serve as a matrix in which the other cells are embedded. [2] Stroma is made of various types of stromal cells. Examples of stroma include: stroma of iris; stroma of cornea; stroma of ovary; stroma of thyroid gland; stroma of thymus; stroma of bone marrow; lymph node stromal cell; multipotent stromal cell ...
Stromal cells, or mesenchymal stromal cells, are differentiating cells found in abundance within bone marrow but can also be seen all around the body. Stromal cells can become connective tissue cells of any organ , for example in the uterine mucosa ( endometrium ), prostate , bone marrow , lymph node and the ovary .
Stroma of ovary, a soft tissue, well supplied with blood, consisting of spindle-shaped cells with a small amount of connective tissue; Stroma of iris, fibres and cells in the iris; Stroma of cornea, plates of collagen fibrils in the cornea; Lymph node stromal cell, cells which provide a scaffold for other lymph node cells; Stroma of bone marrow
Tetherin, also known as bone marrow stromal antigen 2, is a lipid raft associated protein that in humans is encoded by the BST2 gene. [5] [6] [7] In addition, tetherin has been designated as CD317 (cluster of differentiation 317). This protein is constitutively expressed in mature B cells, plasma cells and plasmacytoid dendritic cells, and in ...
Although reticular fibers are widely distributed in the body, reticular tissue is limited to certain sites. It forms a labyrinth-like stroma (literally, "bed or "mattress"), or internal framework, that can support many free blood cells (largely lymphocytes) in lymph nodes, the spleen, and red bone marrow.