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Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, chronic liver failure or chronic hepatic failure and end-stage liver disease, is a condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue and regenerative nodules as a result of chronic liver disease.
Hepatorenal syndrome (HRS) is a life-threatening medical condition that consists of rapid deterioration in kidney function in individuals with cirrhosis or fulminant liver failure. HRS is usually fatal unless a liver transplant is performed, although various treatments, such as dialysis , can prevent advancement of the condition.
[5] [27] In some cases, it can cause symptoms related to liver dysfunction such as fatigue, malaise, and dull right-upper-quadrant abdominal discomfort. Mild yellow discoloration of the skin may occur, although this is rare. [28] MASH can severely impair liver function, leading to cirrhosis, liver failure, and liver cancer. [5]
Cirrhosis. Liver cancer. ... Metabolic syndrome. Dyslipidemia (abnormal levels of lipids, or fats, in your blood) Prostock-Studio / iStock. Symptoms of Fatty Liver Disease.
Differential diagnosis: Wernicke–Korsakoff syndrome, delirium tremens, hypoglycemia, subdural hematoma, hyponatremia [1] Treatment: Supportive care, treating triggers, lactulose, liver transplant [1] [4] Prognosis: Average life expectancy less than a year in those with severe disease [1] Frequency: Affects >40% with cirrhosis [7]
Chronic liver disease takes several years to develop and the condition may not be recognised unless there is clinical awareness of subtle signs and investigation of abnormal liver function tests. Testing for chronic liver disease involves blood tests, imaging including ultrasound, and a biopsy of the liver. The liver biopsy is a simple ...
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