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Finasteride and minoxidil are usually first line therapy for its treatment. Other options include topical or systemic spironolactone or flutamide , although they have a high incidence of feminising side effects and are better tolerated in female androgenic hair loss.
Alfatradiol, also known as 17α-estradiol and sold under the brand names Avicis, Avixis, Ell-Cranell Alpha, and Pantostin, is a weak estrogen and 5α-reductase inhibitor medication which is used topically in the treatment of pattern hair loss (androgenic alopecia or pattern baldness) in men and women.
Topical steroids are the topical forms of corticosteroids. Topical steroids are the most commonly prescribed topical medications for the treatment of rash and eczema . Topical steroids have anti-inflammatory properties and are classified based on their skin vasoconstrictive abilities. [ 1 ]
Minoxidil is a piperidine derivative widely used to prevent hair loss. Piperidine and its derivatives are ubiquitous building blocks in pharmaceuticals [26] and fine chemicals. The piperidine structure is found in, for example: Icaridin (Insect repellent) SSRIs (selective serotonin reuptake inhibitors) Paroxetine; Stimulants and nootropics ...
The strength of topical hydrocortisone products ranges from 0.1% to 2.5%, which means there could be 1 mg to 25 mg hydrocortisone in 1g of the products. [12] Some formulations for topical hydrocortisone include hydrocortisone 0.5% cream or ointment, hydrocortisone 1% cream or ointment, and hydrocortisone 2.5% cream or ointment. [34]
Two FTUs are approximately equivalent to 1 g of topical steroid. One handprint is 0.8% (i.e. approximately 1%) of the total body surface area, [ 3 ] and one FTU covers approximately two handprints. As two FTUs are approximately equivalent to 1g of topical application, the "Rule of Hand" states that "4 hand areas = 2 FTU = 1 g".
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