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Atipamezole. Atipamezole , sold under the brand name Antisedan among others, is a synthetic α 2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with the sedative for α 2 -adrenergic receptors and displacing them.
Medetomidine. Medetomidine is a veterinary anesthetic drug with potent sedative effects and emerging illicit drug adulterant. It is a racemic mixture of two stereoisomers, levomedetomidine and dexmedetomidine, the latter being the isomer with the pharmacologic effect as an alpha 2- adrenergic agonist. Effects can be reversed using atipamezole.
Alpha-2 blockers (or α2 blockers) are a subset of the alpha blocker class of drugs and are antagonists to the α 2 adrenergic receptor. They are mainly used in research, having found limited clinical application in human medicine. They are extensively used in veterinary medicine to reverse the effects of alpha-2 agonist drugs used as sedatives ...
dexamethasone – anti-inflammatory steroid. diazepam – benzodiazepine used to treat status epilepticus, also used as a preanaesthetic and a sedative. dichlorophene – fungicide, germicide, and antimicrobial agent, also used for the removal of parasites. diphenhydramine – histamine blocker. doxycycline – antibiotic, also used to treat ...
Xylazine is a common veterinary drug used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle, and other mammals. [2] In veterinary anesthesia, it is often used in combination with ketamine. Veterinarians also use xylazine as an emetic, especially in cats. [4]
Amitraz (development code BTS27419) is a non-systemic acaricide and insecticide [1] and has also been described as a scabicide. It was first synthesized by the Boots Co. in England in 1969. [2] Amitraz has been found to have an insect repellent effect, works as an insecticide and also as a pesticide synergist. [3]
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