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Z583 (GLXC-26150) is a chemical compound which acts as a potent and highly selective inhibitor of JAK3, and was developed for the treatment of rheumatoid arthritis ...
The beads, also described as "jewels", were made of primitive stone and earthen materials in the early period, but by the end of the Kofun period were made almost exclusively of jade. Magatama originally served as decorative jewelry, but by the end of the Kofun period functioned as ceremonial and religious objects.
Helenite, also known as Mount St. Helens obsidian, emerald obsidianite, and ruby obsidianite, is a glass made from the fused volcanic rock dust from Mount St. Helens and marketed as a gemstone. [1] [2] Helenite was first created accidentally after the eruption of Mount St. Helens in 1980.
Etched carnelian beads have been found from female Saka burials dated 8th-6th century BCE in Pamir, Tajikistan, all likely imported from Ancient Pakistan. [47] Etched carnelian beads, probably manufactured in Iran or Central Asia where found in the tomb of Saka tomb of Arzhan-2, suggesting trade exchanges with the south. [48]
Meanwhile, the stone dagger lay at the waist of the tomb-bearer with its tip pointing towards the feet suggesting that it was attached to the waist of the user. The comma-shaped ornaments were made of amazonite while the tubular bead ere made of jasper and amber while the small circular beads were made of amazonite, crystal or amber.
Carnelian was recovered from Bronze Age Minoan layers at Knossos on Crete in a form that demonstrated its use in decorative arts; [7] this use dates to approximately 1800 BC. Carnelian was used widely during Roman times to make engraved gems for signet or seal rings for imprinting a seal with wax on correspondence or other important documents ...
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