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The first commercially sold sodium hyaluronate had been developed by Endre Alexander Balazs under the brand name of Healon, manufactured by Pharmacia AB in Sweden in 1980. In 1986, sodium hyaluronate was used as an intra-articular injection to treat osteoarthritis of the knee with the product Hyalart/Hyalgan by Fidia of Italy. [27]
Sodium hyaluronate, the sodium salt of hyaluronic acid, a glycosaminoglycan found in various human connective tissue. Microbial hyaluronic acid production, the process by which microorganisms are utilized in fermentation to synthesize hyaluronic acid. Alguronic acid, trade name for a mix of polysaccharides produced by microalgae. Inhibits ...
A systematic review found that hyaluronate might be beneficial for clinical TMD signs in the long term, but that this may be unstable. The effects of hyaluronate may be similar to glucocorticoids. There may be added benefit in arthrocentesis or arthroscopy if intra-articular injections are combined with these procedures.
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This material is composed of crosslinked dextranomer (dextran) microspheres and non-animal stabilized sodium hyaluronate (NASHA) in phosphate-buffered 0.9% sodium chloride solution. [4] The particles are 120 μm in diameter. The material is non-allergenic, non-immunogenic and non-migratory.
A 2016 review found a trend towards benefit in 2016 for lateral epicondylitis. [11] A 2017 review found tentative evidence in Achilles tendinopathy. [12] In 2012, a systematic review studying various injection therapies found that prolotherapy and hyaluronic acid injection therapies were more effective than placebo when treating lateral ...
The intravenous use of a combination of N-acetylglucosamine, pentosan polysulfate and sodium hyaluronate in horses with surgically-induced osteoarthritis saw improvements in X-ray changes to the cartilage but not histologically or in biochemical outcomes, [51] suggesting more evidence is needed for this combination and route of administration.
Sodium hyaluronate is just a salt of hyaluronic acid. The standard preparation for injecting is HY-50 (see the references added to the article). There is another preparation which can be added to the horse's feed. We have ordered this for our horse, as a follow-up to the course of injections, but have not yet received it.
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