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Congenital insensitivity to pain (CIP), also known as congenital analgesia, is one or more extraordinarily rare conditions in which a person cannot feel (and has never felt) physical pain. [1] The conditions described here are separate from the HSAN group of disorders, which have more specific signs and cause.
1960: Ervin and Sternbach describe 6 members from a 2-generation family with dominantly-inherited congenital insensitivity to pain. [ 4 ] 1974: Comings and Amromin describe 3 members from a 2-generation family which consisted of a mother, her son and her daughter with the symptoms characteristic of Marsili syndrome, there was a possibility that ...
Some inhabitants near Gällivare, mainly in the village of Tjautjas (also Tjautjasjaure or Čavččas) 20 km outside Gällivare, have a remarkably high incidence of congenital insensitivity to pain, an extremely rare disease which inhibits the sensation of pain, heat and cold. There have been nearly 40 reported cases in the area.
Vittangi (Swedish pronunciation: [ˈvɪ̌tːaŋɡɪ]; [2] Meänkieli: Vittanki; Northern Sámi: Vazáš) is a locality situated in Kiruna Municipality, Norrbotten County, Sweden with 784 inhabitants in 2010. [1] The village of Vittangi was founded in 1674 by Henrik Mickelsson Kyrö from Pello.
Those affected are unable to feel pain and temperature. [2] [3] The absence of pain experienced by people with CIPA puts them at high risk for accidental self-injury. Corneal ulceration occurs due to a lack of protective impulses. [4] Joint and bone problems are common due to repeated injuries, and wounds heal poorly. [5]
Women in pain are more likely than men to receive prescriptions for sedatives instead of pain medication, and one study found that women who received coronary bypass surgery were half as likely to ...
Familial dysautonomia (FD), also known as Riley–Day syndrome, is a rare, [2] progressive, [3] recessive genetic disorder of the autonomic nervous system [2] that affects the development and survival of sensory, sympathetic, and some parasympathetic neurons in the autonomic and sensory nervous system.
Here are links to possibly useful sources of information about Congenital insensitivity to pain with anhidrosis. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine.