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The pathophysiology of cancer-related fatigue is poorly understood. It may be caused by the cancer or the effects it has on the body, by the body's response to the cancer, or by the cancer treatments. Fatigue is a common symptom of cancer. [3] Some fatigue is caused by cancer treatments. This may show a characteristic pattern.
Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...
Simplified control circuit of human thermoregulation. [8]The core temperature of a human is regulated and stabilized primarily by the hypothalamus, a region of the brain linking the endocrine system to the nervous system, [9] and more specifically by the anterior hypothalamic nucleus and the adjacent preoptic area regions of the hypothalamus.
This contagious skin rash is caused by streptococcus and staphylococcus bacteria that enter the body through compromised skin. Other symptoms to note: Initially, red blisters form at the infection ...
Skin cancer is the most commonly diagnosed form of cancer in humans. [11] [12] [13] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. [1] The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC).
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [2] [7] These contrast with benign tumors, which do not spread. [7] Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. [1]
Inflammation for example has a recognised group of cardinal signs and symptoms, [44] as does exacerbations of chronic bronchitis, [45] and Parkinson's disease. In contrast to a pathognomonic cardinal sign, the absence of a sign or symptom can often rule out a condition. This is known by the Latin term sine qua non.
Chronic fatigue with a known cause is twice as common as idiopathic chronic fatigue. [6] Idiopathic chronic fatigue affects between 2.4% and 6.42% of patients, [26] with females more likely to be affected than men. [1] Age at onset is typically over 50 years of age. [13]