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Keratin, type II cytoskeletal 7 also known as cytokeratin-7 (CK-7) or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded by the KRT7 gene. [5] [6] [7] Keratin 7 is a type II keratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.
Vascular dementia; Other names: Dementia due to cerebrovascular disease; [1] Vascular cognitive impairment [2] Brain atrophy from vascular dementia: Specialty: Psychiatry, neurology Symptoms: Cognitive impairment, short-term memory loss [3] Complications: Heart disease, loss of ability to care for self and interact, pneumonia [4] Causes
The term cytokeratin began to be used in the late 1970s, when the protein subunits of keratin intermediate filaments inside cells were first being identified and characterized. [2] In 2006 a new systematic nomenclature for mammalian keratins was created, and the proteins previously called cytokeratins are simply called keratins (human ...
Because of this, the specific names of these types of this dementia, including Binswanger's disease were lost. [4] This was until 1992 when Alzheimer's diagnostic centers created specific criteria known as the Hachinski Ischemic Scale (after Dr. Vladimir Hachinski) which became the standard for diagnosing MID or vascular dementia. [21]
CAA is associated with brain hemorrhages, particularly microhemorrhages.The accumulation of amyloid beta peptide deposits in the blood vessel walls results in damage of the blood vessels and hindrance of normal blood flow, making blood vessels more prone to bleeding [10] Since CAA can be caused by the same amyloid protein that is associated with Alzheimer's dementia, brain bleeds [11] are more ...
Pre-dementia or early-stage dementia (stages 1, 2, and 3). In this initial phase, a person can still live independently and may not exhibit obvious memory loss or have any difficulty completing ...
Long term [4] Causes: Unknown [4] Diagnostic method: Based on symptoms and biomarkers [1] Differential diagnosis: Alzheimer's, Parkinson's disease dementia, certain mental illnesses, vascular dementia [5] Medication: Donepezil, rivastigmine and memantine; [6] melatonin [7] Prognosis: Variable; average survival 4 years from diagnosis [8] Frequency
Vertebrobasilar insufficiency (VBI) describes a temporary set of symptoms due to decreased blood flow in the posterior circulation of the brain.The posterior circulation supplies the medulla, pons, midbrain, cerebellum and (in 70-80% of people) supplies the posterior cerebellar artery to the thalamus and occipital cortex. [1]