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The first member of this family to be characterized was a respiratory epithelium, Ca 2+-regulated, chloride channel protein isolated from bovine tracheal apical membranes. [9] It was biochemically characterized as a 140 kDa complex. The bovine EClC protein has 903 amino acids and four putative transmembrane segments.
Chloride intracellular channel 4, also known as CLIC4,p644H1,HuH1, is a eukaryotic gene. [5]Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume.
Chloride intracellular channel protein 1 is a protein that in humans is encoded by the CLIC1 gene. [5] [6]Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume.
The Calcium-Dependent Chloride Channel (Ca-ClC) proteins (or calcium-activated chloride channels (CaCCs), [2] are heterogeneous groups of ligand-gated ion channels for chloride that have been identified in many epithelial and endothelial cell types as well as in smooth muscle cells.
Chloride channels: This superfamily of channels consists of approximately 13 members. They include ClCs, CLICs, Bestrophins and CFTRs. These channels are non-selective for small anions; however chloride is the most abundant anion, and hence they are known as chloride channels. Potassium channels. Voltage-gated potassium channels e.g., Kvs, Kirs ...
Chloride channel protein, skeletal muscle (CLCN1) is a protein that in humans is encoded by the CLCN1 gene. [6] Mutations in this protein cause congenital myotonia. CLCN1 is critical for the normal function of skeletal muscle cells. For the body to move normally, skeletal muscles must tense (contract) and relax in a coordinated way.
23844 Ensembl ENSG00000016490 ENSMUSG00000028255 UniProt A8K7I4 Q9D7Z6 RefSeq (mRNA) NM_001285 NM_017474 RefSeq (protein) NP_001276 NP_059502 Location (UCSC) Chr 1: 86.47 – 86.5 Mb Chr 3: 144.71 – 144.74 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene. This gene encodes a member of the calcium ...
Chloride intracellular channel protein 5 is a protein that in humans is encoded by the CLIC5 gene. [5] [6] Expression and localization. CLIC5 exists in two ...
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