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The area becomes dusky and a shallow open sore forms as the skin around the bite dies . It is the only proven type of necrotic arachnidism in humans. [1] [a] While there is no known therapy effective for loxoscelism, there has been research on antibiotics, surgical timing, hyperbaric oxygen, potential antivenoms and vaccines. [1]
Bites most often occur as a defense when the spider is trapped against the skin, in clothing, for example. [8] The total volume of venom is minute (only 2 micrograms injected out of 4 microliters in the venom glands). [17] The bite of a recluse spider can generally be categorized into one of the following groups: [8]
While the majority of brown recluse spider bites do not result in any symptoms, cutaneous symptoms occur more frequently than systemic symptoms. In such instances, the bite forms a necrotizing ulcer as the result of soft tissue destruction and may take months to heal, leaving deep scars. These bites usually become painful and itchy within 2–8 ...
The family was first described by Eugen von Keyserling in 1880, [3] and treated as a subfamily and synonym of "Loxoscelidae" in 1893, [7] though this violates the rules of the International Code of Zoological Nomenclature; the publication of Sicariidae in 1880 predates the publication of Loxoscelidae in 1893, and the older name therefore has ...
This lack of a cure or vaccine is a definite problem in the equine industry, especially in developing countries where equines are highly valuable for both agriculture and transportation. [5] Dourine is considered an endemic problem in developing countries, where over sixty percent of equines in the world are located. [ 4 ]
The principle of antivenom is based on that of vaccines, developed by Edward Jenner; however, instead of inducing immunity in the person directly, it is induced in a host animal and the hyperimmunized serum is transfused into the person. [20] The host animals may include horses, donkeys, goats, sheep, rabbits, chickens, llamas, and camels. [21]
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