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The area becomes dusky and a shallow open sore forms as the skin around the bite dies . It is the only proven type of necrotic arachnidism in humans. [1] [a] While there is no known therapy effective for loxoscelism, there has been research on antibiotics, surgical timing, hyperbaric oxygen, potential antivenoms and vaccines. [1]
Cutaneous loxoscelism results from serious bites causing a necrotising skin ulcer in about 50% of bites [12] with destruction of soft tissue and may take months, and rarely years to heal, leaving deep scars. The damaged tissue will become gangrenous black and eventually slough away. Initially there may be no pain from a bite, but over time the ...
In such instances, the bite forms a necrotizing ulcer as the result of soft tissue destruction and may take months to heal, leaving deep scars. These bites usually become painful and itchy within 2–8 hours. Pain and other local effects worsen 12–36 hours after the bite, and the necrosis develops over the next few days. [30]
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Bites most often occur as a defense when the spider is trapped against the skin, in clothing, for example. [8] The total volume of venom is minute (only 2 micrograms injected out of 4 microliters in the venom glands). [17] The bite of a recluse spider can generally be categorized into one of the following groups: [8]
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An average bite requires 12 vials," a KGTV reporter said. "Right now, vials cost about $5,000 a piece to the patient," Dr. Richard Clark from UCSD's Poison Control Center said.
The damaged tissue will become black and eventually slough away. Bites occur commonly during dressing as spiders are trapped in the sleeve or pant leg. Bites usually become painful and itchy within 2 to 8 hours, pain and other local effects worsen 12 to 36 hours after the bite with the necrosis developing over the next few days. [31]