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Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...
Commonly, cholesterol tests measure the amount of low-density lipoprotein (LDL), which is commonly known as "bad cholesterol," and high-density lipoprotein (HDL) cholesterol. Some doctors say that ...
Its collection of nutritional compounds help protect against cardiovascular diseases, induce a vasodilatory effect (i.e., they cause your blood vessels to dilate, reducing blood pressure), and ...
A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism.In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout. [1]
Dark chocolate is rich in flavanols, a natural compound that can lower blood pressure, reducing the risk of stroke and heart disease, adds Frances Largeman-Roth, a registered dietitian. She ...
It decreases LDL by 15–30% and raises HDL by 3–5%, with little effect on triglycerides, but can cause a slight increase. Bile acid sequestrants may cause gastrointestinal problems and may also reduce the absorption of other drugs and vitamins from the gut. Ezetimibe is a selective inhibitor of dietary cholesterol absorption.
"The consumption of caffeinated green tea has demonstrated efficacy in lowering blood pressure for individuals with prehypertension and stage 1 hypertension, signaling potential benefits in blood ...
URAT1 is the central mediator in the transport of uric acid from the kidney into the blood. In some persons with loss-of-function mutations of URAT1, the uricosurics benzbromarone and losartan had no effect, suggesting these drugs act on URAT1 in vivo. [1] Thus, uricosuric drugs may be candidates for management in a personalized medicine model.