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[78] [79] This feature confines far-UVC exposure to the superficial layers of tissue, such as the outer layer of dead skin (the stratum corneum) and the tear film and surface cells of the cornea. [ 22 ] [ 80 ] [ 81 ] [ 82 ] As these tissues do not contain replicating cells, damage to them poses less carcinogenic risk.
The location of 'far-UVC' radiation (200-235 nm) in the electromagnetic spectrum. Far-UVC is a type of ultraviolet germicidal irradiation being studied and commercially developed for its combination of pathogen inactivation properties and reduced negative effects on human health when used within exposure guidelines.
Light therapy for skin conditions like psoriasis usually use 313 nanometer UVB though it may use UVA (315–400 nm wavelength) or a broader spectrum UVB (280–315 nm wavelength). UVA combined with psoralen, a drug taken orally, is known as PUVA treatment. In UVB phototherapy the exposure time is very short, seconds to minutes depending on ...
Both UVA and UVB destroy vitamin A in skin, which may cause further damage. [61] UVB radiation can cause direct DNA damage. [62] This cancer connection is one reason for concern about ozone depletion and the ozone hole. The most deadly form of skin cancer, malignant melanoma, is mostly caused by DNA damage independent from UVA radiation.
To the hands and legs PUVA may be more effective. The reason can be because UVA penetrates deeper in the skin, and the melanocytes in the skin of the hands and legs are positioned deeper in the skin. Narrowband UVB 311 nanometer is blocked by the topmost skin layer, and UVA 365 nanometer reaches the melanocytes that are in the bottom skin layer.
Tissue clearing refers to a group of chemical techniques used to turn tissues transparent. [ 1 ] [ 2 ] [ 3 ] By turning tissues transparent to certain wavelengths of light, it allows one to gain optical access to a tissue. [ 1 ]
CBD may have potential protective benefits against UVA radiation, which causes aging and can lead to cancer, when used alongside sunscreen, a new study suggests. CBD may help prevent sun damage ...
PUVA means UVA + psoralen. It consists of irradiation of the skin with the UVA ultraviolet light, from a fluorescent bulb or LED lamps. Tanning beds are used both in dermatology practices for the treatment of cosmetic skin conditions (such as psoriasis, acne, eczema and vitiligo) and in indoor tanning salons for cosmetic tanning.