Search results
Results from the WOW.Com Content Network
Chelation (/ k iː ˈ l eɪ ʃ ən /) is a type of bonding of ions and their molecules to metal ions. It involves the formation or presence of two or more separate coordinate bonds between a polydentate (multiple bonded) ligand and a single central metal atom.
DOTA is derived from the macrocycle known as cyclen.The four secondary amine groups are modified by replacement of the N-H centers with N-CH 2 CO 2 H groups. The resulting aminopolycarboxylic acid, upon ionization of the carboxylic acid groups, is a high affinity chelating agent for di- and trivalent cations.
The structure of the complex of sodium (Na +) and the antibiotic monensin A Structure of a potassium complex of a crown ether, a synthetic ionophore-ion complex. Biological activities of metal ion-binding compounds can be changed in response to the increment of the metal concentration, and based on the latter compounds can be classified as "metal ionophores", "metal chelators" or "metal ...
DOTA (chelator) derivatives (6 P) S. Sequestrants (1 P) Siderophores (23 P) Pages in category "Chelating agents" The following 164 pages are in this category, out of ...
TPEN (N,N,N ′,N ′-tetrakis(2-pyridinylmethyl)-1,2-ethanediamine [1]) is an intracellular membrane-permeable ion chelator. [2] TPEN has a high affinity for many transition metals and should not be considered specific or selective for a particular ion. Chelators can be used in chelation therapy to remove toxic metals in the body. TPEN is a ...
Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. [1] Chelation therapy has a long history of use in clinical toxicology [2] and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of ...
EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid), also known as egtazic acid (INN, USAN), [2] is an aminopolycarboxylic acid, a chelating agent.
EDDHA or ethylenediamine-N,N ′-bis(2-hydroxyphenylacetic acid) is a chelating agent.Like EDTA, it binds metal ions as a hexadentate ligand, using two amines, two phenolate centers, and two carboxylates as the six binding sites.