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Intestinal villi (sg.: villus) are small, finger-like projections that extend into the lumen of the small intestine. Each villus is approximately 0.5–1.6 mm in length (in humans), and has many microvilli projecting from the enterocytes of its epithelium which collectively form the striated or brush border. Each of these microvilli are about 1 ...
Goblet cells secrete mucus, which lubricates the passage of food along and protects the intestinal wall from digestive enzymes. In the small intestine, villi are folds of the mucosa that increase the surface area of the intestine. The villi contain a lacteal, a vessel connected to the lymph system that aids in the removal of lipids and tissue ...
Micrograph of the small intestine mucosa showing the intestinal villi and crypts of Lieberkühn. The three sections of the small intestine look similar to each other at a microscopic level, but there are some important differences. The parts of the intestine are as follows: This cross section diagram shows the 4 layers of the small intestine wall.
The villi of the jejunum look like long, finger-like projections, and are a histologically identifiable structure. While the length of the entire intestinal tract contains lymphoid tissue , only the ileum has abundant Peyer's patches , which are unencapsulated lymphoid nodules that contain large numbers of lymphocytes and immune cells, like ...
The barrier formed by the intestinal epithelium separates the external environment (the contents of the intestinal lumen) from the body [15] and is the most extensive and important mucosal surface of body. [18] The intestinal epithelium serves several crucial functions, exhibiting both innate and adaptive immune features.
Illustration of the brush border membrane of small intestinal villi. A brush border (striated border or brush border membrane) is the microvillus-covered surface of simple cuboidal and simple columnar epithelium found in different parts of the body. Microvilli are approximately 100 nanometers in diameter and their length varies from ...
In the intestinal tract the immune system must have tolerance to the normal intestinal flora, yet respond to pathogenic microorganisms. Imbalance of this causes inflammation diseases such as inflammatory bowel disease. [10] The lamina propria’s richness in macrophages and lymphoid cells makes it a key place for immune responses to occur.
The cells were first noted by Henle in 1837 when studying the lining of the small intestine, seen to be mucus producing by Leydig in 1857 (who was examining the epidermis of fish), and were given their name by Schulze in 1867, [24] [25] Schulze chose the descriptive name "goblet" because of the shape of the cell, rather than a functional name ...