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Drugs used to prevent migraine in the UK include: fremanezumab, eptinezumab, erenumab, galcanezumab, botulinium toxin A, topiramate. A meta-analysis suggested that all these drugs reduced the number of days people spent with migraine and that differences in effectiveness between these drugs were modest. [26] [27]
Antimigraine drugs are medications intended to reduce the effects or intensity of migraine headache. They include drugs for the treatment of acute migraine symptoms as well as drugs for the prevention of migraine attacks.
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
Methysergide is used exclusively to treat episodic and chronic migraine and for episodic and chronic cluster headaches. [12] Methysergide is one of the most effective [13] medications for the prevention of migraine, but is not intended for the treatment of an acute attack, it is to be taken daily as a preventative medication.
Multiple sources recommend multimodal treatment, which is a combination of medicinal and non-medicinal remedies. [5] Some treatments are controversial and are still being tested for effectiveness. Suggested treatments for chronic headaches include medication, physical therapy, acupuncture, relaxation training, and biofeedback.
Atogepant, sold under the brand name Qulipta among others, is a medication used to prevent migraines. [4] [5] It is a gepant, an orally active calcitonin gene-related peptide receptor antagonist. [4] [7] The most common side effects include nausea, constipation, tiredness, somnolence (sleepiness), decreased appetite, and decreased weight. [5]
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