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Extranodal NK/T-cell lymphoma, nasal type (ENKTCL-NT) (also termed angiocentric lymphoma, nasal-type NK lymphoma, NK/T-cell lymphoma, polymorphic/malignant midline reticulosis, [3] and lethal midline granuloma [4]) is a rare type of lymphoma that commonly involves midline areas of the nasal cavity, oral cavity, and/or pharynx [5] At these sites, the disease often takes the form of massive ...
Date: 25 June 2021: Source: Image source: Takahara M, Kumai T, Kishibe K, Nagato T, Harabuchi Y (2021)."Extranodal NK/T-Cell Lymphoma, Nasal Type: Genetic, Biologic, and Clinical Aspects with a Central Focus on Epstein-Barr Virus Relation.
While EBV preferentially infects B cells, it may also infect other lymphocyte types viz., CD4+ T cells (i.e. T helper cells), CD8+ cells (i.e. cytotoxic T cells), NK cells (i.e. natural killer cells). The mechanism by which EBV infects these other cell types is unknown but may be their direct movement from B cells that are infected with the virus.
Certain lymphomas (extranodal NK/T-cell lymphoma, nasal type and type II enteropathy-associated T-cell lymphoma) can be mimicked by two benign diseases that involve the excessive proliferation of nonmalignant NK cells in the GI tract, natural killer cell enteropathy, a disease wherein NK cell infiltrative lesions occur in the intestine, colon ...
ENKTCL-NT is a rare type of lymphoma that commonly involves the nasal cavity, oral cavity, and/or pharynx [5] but less commonly can also involve the eye, larynx, lung, gastrointestinal tract, skin, and various other tissues. [6] Patients presenting with highly localized midline facial disease fit the historical definition of lethal midline ...
T-cell lymphoma is a rare form of cancerous lymphoma affecting T-cells. [1] Lymphoma arises mainly from the uncontrolled proliferation of lymphocytes, such as T-cells, and can become cancerous. [2] T-cell lymphoma is categorized under Non-Hodgkin lymphoma (NHL) and represents less than 15% of all Non-Hodgkin's diseases in the category. [3]
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Peripheral T-cell lymphoma refers to a group of T-cell lymphomas that develop away from the thymus [citation needed] or bone marrow. [1] Examples include: [2] Cutaneous T-cell lymphomas; Angioimmunoblastic T-cell lymphoma; Extranodal natural killer/T-cell lymphoma, nasal type; Enteropathy type T-cell lymphoma; Subcutaneous panniculitis-like T ...