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Sp100 nuclear antigen is an interferon stimulated antigen found in the cell nuclei of many human and higher animal cells. Autoantibodies directed against Sp100 are often found in patients with primary biliary cirrhosis. [1] Histologically Sp100 'dots' regions of the cell nucleus. Viral infection and mitogens affect the expression of the Sp100 ...
Anti-sp100 antibodies are found in association with primary biliary cirrhosis. [1] The autoimmune target of anti-sp100 is the sp100 nuclear antigen which was identified by its association with primary biliary cirrhosis. 20-30% of patients with primary biliary cirrhosis have sp100 Abs. The sera of these patients exhibit a characteristic "nuclear ...
Anti-sp100 antibodies are found in approximately 20–30% of primary biliary cirrhosis (PBC). They are found in few individuals without PBC, and therefore are a very specific marker of the disease. The sp100 antigen is found within nuclear bodies; large protein complexes in the nucleus that may have a role in cell growth and differentiation. [47]
Oak Creek is a city in Milwaukee County, Wisconsin, United States. It sits on the southwestern shore of Lake Michigan and is located immediately south of Milwaukee. The population was 36,497 at the 2020 census. The city is one of the fastest growing in Milwaukee County and all of Wisconsin. [7]
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(The Center Square) – President-elect Donald Trump, who is set to take office Monday, has made a series of promises of major executive actions on “day one” in office. One of the simplest and ...
U.S. farm industry groups want President-elect Donald Trump to spare their sector from his promise of mass deportations, which could upend a food supply chain heavily dependent on immigrants in ...
The Milwaukee County Historical Society, also known as MCHS, is a local historical society in Milwaukee County, Wisconsin. Founded in 1935, the organization was formed to preserve, collect, recognize, and make available materials related to Milwaukee County history. It is located in downtown Milwaukee in the former Second Ward Savings Bank ...
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