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Due to the lack of studies, decongestants in combination drugs or isolated forms are suggested to be used sparingly during pregnancy. Saline nasal sprays, among other non-pharmacological treatments, are considered to be safe alternatives for decongestants.
Common side effects for oral decongestants include insomnia, hypertension (elevated blood pressure), and difficulty in urination. [12] Avoid use during pregnancy as it may cause vasoconstriction of uterine arteries thus reducing fetal blood supply. [14] Zyrtec-D, an example of combination therapy. Combination therapy with antihistamines
[4] [5] Use is not recommended during pregnancy. [2] Xylometazoline is in the decongestant and alpha-adrenergic agonist families of medication. [5] [6] One study classified it with selectivity ratios in alpha 2 adrenergic receptors of 151 for a2A vs a2B, 4.5 a2A vs a2C, and 33.9 a2B vs a2C. Making it a highly selective a2A agonist. [7]
Pseudoephedrine is the most common oral decongestant alternative, but since it has potential for abuse, you’ll likely need to ask a pharmacist for help accessing it behind the counter.
Use during pregnancy appears to be safe but has not been well studied. [7] It is not recommended in children less than two years old. [6] It is in the second-generation antihistamine family of medication. [5] Loratadine was patented in 1980 and came to market in 1988. [8] It is on the World Health Organization's List of Essential Medicines. [9]
Pregnancy is an exciting time for many expecting parents, but it can also be a time of many changes and possible health concerns. One such condition that can occur during pregnancy is hearing loss ...
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