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In the mammalian kidney, the regeneration of the tubular component following an acute injury is well known. Recently regeneration of the glomerulus has also been documented. Following an acute injury, the proximal tubule is damaged more, and the injured epithelial cells slough off the basement membrane of the nephron.
The potential for regeneration in mature kidneys is limited [37] [38] because new nephrons cannot be formed. [39] But in cases of limited injury, renal function can be restored through compensatory mechanisms. [40] The kidneys can have noninfectious and infectious diseases; in rare cases, congenital and hereditary anomalies occur in the kidneys ...
This illustration demonstrates the normal kidney physiology, including the Proximal Convoluted Tubule (PCT), Loop of Henle, and Distal Convoluted Tubule (DCT). It also includes illustrations showing where some types of diuretics act, and what they do. Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney.
AKI - the other main type of kidney disease - can be caused by dehydration, blood loss, urinary tract obstructions such as kidney stones or blood clots, low blood pressure, or heart disease. It ...
Multipotent mouse kidney progenitor cells (MKPC) were obtained from Myh9 targeted mutant mice. Injection of MKPC into mice post-ischemic injury saw the MKPC regenerating different cell lineages and was able to regenerate renal function and enhanced survival.
The shape of the kidneys varies between reptiles due to variations of their body form. [8] The kidneys of snakes are elongated, cylindrical [53] [50] and lobulated. [52] Turtles and some lizards have urinary bladder [50] that opens into the cloaca [54] but snakes and crocodiles do not have it. [50]
In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs [1] that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. [ 2 ] [ 3 ] They are located on the left and right in the retroperitoneal space , and in adult humans are about 12 centimetres ( 4 + 1 ⁄ 2 inches) in ...
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