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  2. Zaytsev's rule - Wikipedia

    en.wikipedia.org/wiki/Zaytsev's_rule

    For example, when 2-iodobutane is treated with alcoholic potassium hydroxide (KOH), but-2-ene is the major product and but-1-ene is the minor product. [ 1 ] More generally, Zaytsev's rule predicts that in an elimination reaction the most substituted product will be the most stable, and therefore the most favored.

  3. Electrophilic aromatic directing groups - Wikipedia

    en.wikipedia.org/wiki/Electrophilic_aromatic...

    The methyl group in toluene is small and will lead the ortho product being the major product. On the other hand, the t-butyl group is very bulky (there are 3 methyl groups attached to a single carbon) and will lead the para product as the major one. Even with toluene, the product is not 2:1 but having a slightly less ortho product.

  4. p-Xylene - Wikipedia

    en.wikipedia.org/wiki/P-Xylene

    p-Xylene (para-xylene) is an aromatic hydrocarbon. It is one of the three isomers of dimethylbenzene known collectively as xylenes . The p- stands for para- , indicating that the two methyl groups in p -xylene occupy the diametrically opposite substituent positions 1 and 4.

  5. Syn and anti addition - Wikipedia

    en.wikipedia.org/wiki/Syn_and_anti_addition

    The concepts of syn and anti addition are used to characterize the different reactions of organic chemistry by reflecting the stereochemistry of the products in a reaction. The type of addition that occurs depends on multiple different factors of a reaction, and is defined by the final orientation of the substituents on the parent molecule.

  6. Arene substitution pattern - Wikipedia

    en.wikipedia.org/wiki/Arene_substitution_pattern

    The prefixes ortho, meta, and para are all derived from Greek, meaning correct, following, and beside, respectively. The relationship to the current meaning is perhaps not obvious. The ortho description was historically used to designate the original compound, and an isomer was often called the meta compound.

  7. Hammett equation - Wikipedia

    en.wikipedia.org/wiki/Hammett_equation

    The basic idea is that for any two reactions with two aromatic reactants only differing in the type of substituent, the change in free energy of activation is proportional to the change in Gibbs free energy. [5] This notion does not follow from elemental thermochemistry or chemical kinetics and was introduced by Hammett intuitively. [a]

  8. Markovnikov's rule - Wikipedia

    en.wikipedia.org/wiki/Markovnikov's_rule

    The major product of the addition reaction will be the one formed from the more stable intermediate. Therefore, the major product of the addition of HX (where X is some atom more electronegative than H) to an alkene has the hydrogen atom in the less substituted position and X in the more substituted position.

  9. Law of mass action - Wikipedia

    en.wikipedia.org/wiki/Law_of_mass_action

    Specifically, it implies that for a chemical reaction mixture that is in equilibrium, the ratio between the concentration of reactants and products is constant. [2] Two aspects are involved in the initial formulation of the law: 1) the equilibrium aspect, concerning the composition of a reaction mixture at equilibrium and 2) the kinetic aspect ...