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  2. Fixed allele - Wikipedia

    en.wikipedia.org/wiki/Fixed_allele

    In population genetics, a fixed allele is an allele that is the only variant that exists for that gene in a population. A fixed allele is homozygous for all members of the population. [1] The process by which alleles become fixed is called fixation. For this hypothetical species, the population in the topmost frame exhibits no fixed allele for ...

  3. Fixation (population genetics) - Wikipedia

    en.wikipedia.org/wiki/Fixation_(population_genetics)

    In the process of substitution, a previously non-existent allele arises by mutation and undergoes fixation by spreading through the population by random genetic drift or positive selection. Once the frequency of the allele is at 100%, i.e. being the only gene variant present in any member, it is said to be "fixed" in the population. [1]

  4. Allele - Wikipedia

    en.wikipedia.org/wiki/Allele

    An allele [1] is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. [ 2 ] Alleles can differ at a single position through single nucleotide polymorphisms (SNP), [ 3 ] but they can also have insertions and deletions of up to several thousand base pairs .

  5. Selective sweep - Wikipedia

    en.wikipedia.org/wiki/Selective_sweep

    In genetics, a selective sweep is the process through which a new beneficial mutation that increases its frequency and becomes fixed (i.e., reaches a frequency of 1) in the population leads to the reduction or elimination of genetic variation among nucleotide sequences that are near the mutation.

  6. Glossary of genetics and evolutionary biology - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_genetics_and...

    (of a gene or allele) Traceable back through an arbitrary number of generations without mutation to a common ancestor of the group of descendant organisms that carries the gene or allele. [1] A gene or allele present in a group of descendant organisms is said to be identical by descent to a gene or allele in a common ancestor of the group if ...

  7. Genotype frequency - Wikipedia

    en.wikipedia.org/wiki/Genotype_frequency

    The Hardy–Weinberg law describes the relationship between allele and genotype frequencies when a population is not evolving. Let's examine the Hardy–Weinberg equation using the population of four-o'clock plants that we considered above: if the allele A frequency is denoted by the symbol p and the allele a frequency denoted by q, then p+q=1.

  8. Selection coefficient - Wikipedia

    en.wikipedia.org/wiki/Selection_coefficient

    Selection coefficient, usually denoted by the letter s, is a measure used in population genetics to quantify the relative fitness of a genotype compared to other genotypes. . Selection coefficients are central to the quantitative description of evolution, since fitness differences determine the change in genotype frequencies attributable to selecti

  9. Monoallelic gene expression - Wikipedia

    en.wikipedia.org/wiki/Monoallelic_Gene_Expression

    [7] [8] XCI is a chromosome-wide monoallelic expression, that includes expression of all genes that are located on X chromosome, in contrast to autosomal RME (aRME) that relates to single genes that are interspersed over the genome. aRME's can be fixed [9] or dynamic, depending whether or not the allele-specific expression is conserved in ...