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The exposome is a concept used to describe environmental exposures that an individual encounters throughout life, and how these exposures impact biology and health. It encompasses both external and internal factors, including chemical, physical, biological, and social factors that may influence human health.
The Toxin and Toxin-Target Database (T3DB), [1] [2] also known as the Toxic Exposome Database, is a freely accessible online database of common substances that are toxic to humans, along with their protein, DNA or organ targets. The database currently houses nearly 3,700 toxic compounds or poisons described by nearly 42,000 synonyms.
Exposure science is the study of the contact between humans (and other organisms) and harmful agents within their environment – whether it be chemical, physical, biological, behavioural or mental stressors – with the aim of identifying the causes and preventions of the adverse health effects they result in. [1] [2] This can include exposure within the home, workplace, outdoors or any other ...
The exposome encompasses the set of human environmental (i.e. non-genetic) exposures from conception onwards, complementing the genome. The exposome was first proposed in 2005 by cancer epidemiologist Christopher Paul Wild in an article entitled "Complementing the genome with an "exposome": the outstanding challenge of environmental exposure ...
Exposome-NL is a 10-year Dutch research program of multiple Dutch universities collaborating in the field of exposome research. Researchers from fields such as exposure science, environmental science, cardiovascular and metabolic health, clinical epidemiology, nutritional epidemiology, geosciences, agent-based modelling, molecular biology, chemistry and bioinformatics, and biostatistics ...
A non-biological entity with a cellular organizational structure (also known as a cellular organization, cellular system, nodal organization, nodal structure, et cetera) is set up in such a way that it mimics how natural systems within biology work, with individual 'cells' or 'nodes' working somewhat independently to establish goals and tasks ...
Eusociality (Greek εὖ eu 'good' and social) is the highest level of organization of sociality. It is defined by the following characteristics: cooperative brood care (including care of offspring from other individuals), overlapping generations within a colony of adults , and a division of labor into reproductive and non-reproductive groups.
He defined a system component as "a unit of organization; a part with a function, i.e., a definite relation between part and whole." He identified the "nonfractionability of components in an organism" as the fundamental difference between living systems and "biological machines." He summarised his views in his book Life Itself. [19]