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The exposome is a concept used to describe environmental exposures that an individual encounters throughout life, and how these exposures impact biology and health. It encompasses both external and internal factors, including chemical, physical, biological, and social factors that may influence human health. [1] [2] [3]
The Toxin and Toxin-Target Database (T3DB), [1] [2] also known as the Toxic Exposome Database, is a freely accessible online database of common substances that are toxic to humans, along with their protein, DNA or organ targets. The database currently houses nearly 3,700 toxic compounds or poisons described by nearly 42,000 synonyms.
Exposome-NL is a 10-year Dutch research program of multiple Dutch universities collaborating in the field of exposome research. Researchers from fields such as exposure science, environmental science, cardiovascular and metabolic health, clinical epidemiology, nutritional epidemiology, geosciences, agent-based modelling, molecular biology, chemistry and bioinformatics, and biostatistics ...
The exposome encompasses the set of human environmental (i.e. non-genetic) exposures from conception onwards, complementing the genome. The exposome was first proposed in 2005 by cancer epidemiologist Christopher Paul Wild in an article entitled "Complementing the genome with an "exposome": the outstanding challenge of environmental exposure ...
Exposure science is the study of the contact between humans (and other organisms) and harmful agents within their environment – whether it be chemical, physical, biological, behavioural or mental stressors – with the aim of identifying the causes and preventions of the adverse health effects they result in. [1] [2] This can include exposure within the home, workplace, outdoors or any other ...
Parts-per-million cube of relative abundance by mass of elements in an average adult human body down to 1 ppm. About 99% of the mass of the human body is made up of six elements: oxygen, carbon, hydrogen, nitrogen, calcium, and phosphorus. Only about 0.85% is composed of another five elements: potassium, sulfur, sodium, chlorine, and magnesium ...
Exposure assessment is a branch of environmental science and occupational hygiene that focuses on the processes that take place at the interface between the environment containing the contaminant of interest and the organism being considered.
While kassinin is not synthesized in the human CNS and PNS, it has been reported via exposure to external elements and can hence be considered a component of the human exposome, [8] which, given the greater extent of homology in human and rate genome justified to growing interest in the neuropeptide.