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Fluphenazine, sold under the brand name Prolixin among others, is a high-potency typical antipsychotic medication. [2] It is used in the treatment of chronic psychoses such as schizophrenia , [ 2 ] [ 3 ] and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine . [ 4 ]
The first LAI antipsychotics (often referred to as simply "LAIs") were the typical antipsychotics fluphenazine and haloperidol. [18] Both fluphenazile and haloperidol are formulated as decanoates , referring to the attachment of a decanoic acid group to the antipsychotic molecule. [ 18 ]
Perphenazine is used to treat psychosis (e.g. in people with schizophrenia and the manic phases of bipolar disorder and OCD). Perphenazine effectively treats the positive symptoms of schizophrenia, such as hallucinations and delusions, but its effectiveness in treating the negative symptoms of schizophrenia, such as flattened affect and poverty of speech, is unclear.
Trifluoperazine, marketed under the brand name Stelazine among others, is a typical antipsychotic primarily used to treat schizophrenia. [3] It may also be used short term in those with generalized anxiety disorder but is less preferred to benzodiazepines. [3]
Flupentixol (), also known as flupenthixol (former BAN), marketed under brand names such as Depixol and Fluanxol is a typical antipsychotic drug of the thioxanthene class. It was introduced in 1965 by Lundbeck.
Pharmacokinetics of long-acting injectable antipsychotics; Medication Brand name Class Vehicle Dosage T max t 1/2 single t 1/2 multiple logP c Ref Aripiprazole lauroxil: Aristada: Atypical
Bifeprunox (code name DU-127,090) is an atypical antipsychotic which, similarly to aripiprazole, combines minimal D 2 receptor agonism with serotonin receptor agonism. [1] It was under development for the treatment of schizophrenia, psychosis and Parkinson's disease.
Outcome Findings in words Findings in numbers Quality of evidence Global outcome Leaving the study early Follow up: 6 weeks to 5 months: Fluspirilene decanoate may increase the risk of leaving the study (reasons not specified), but, the difference is not clear between people given fluspirilene decanoate and those receiving oral antipsychotics.
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261