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Phosphate supplementation is often required in people who have undergone surgery and in chronically malnourished people. [1] Sodium phosphate and potassium phosphate can be administered intravenously or orally. Tablets combining the forms are also available. [2] Phosphate is primary excreted in the urine, at the distal renal tubule. [3]
Sucroferric oxyhydroxide, sold under the brand name Velphoro, is a non-calcium, iron-based phosphate binder used for the control of serum phosphorus levels in adults with chronic kidney disease (CKD) on hemodialysis (HD) or peritoneal dialysis (PD). [6] It is used in form of chewable tablets. [5]
Sodium dihydrogen phosphate Sodium hydrogen phosphate Trisodium phosphate. A sodium phosphate is a generic variety of salts of sodium (Na +) and phosphate (PO 3− 4). Phosphate also forms families or condensed anions including di-, tri-, tetra-, and polyphosphates. Most of these salts are known in both anhydrous (water-free) and hydrated forms ...
The use of Phospho soda has been known to lead to acute phosphate nephropathy. According to the U.S. Food and Drug Administration (FDA), "Acute phosphate nephropathy is a form of acute kidney injury that is associated with deposits of calcium-phosphate crystals in the renal tubules that may result in permanent renal function impairment.
The oral LD 50 is 500 mg/kg. Symptoms of overdose include coma, tachycardia, stupor, and vomiting. The lowest dose without the presence of other medicines which caused death was 15 grams. Mixed with other medicines, a death at 7.5 grams has also occurred. Diflunisal usually comes in 250 or 500 mg, making it relatively hard to overdose by accident.
Sodium hypophosphite (NaPO 2 H 2, also known as sodium phosphinate) is the sodium salt of hypophosphorous acid and is often encountered as the monohydrate, NaPO 2 H 2 ·H 2 O. It is a solid at room temperature, appearing as odorless white crystals. It is soluble in water, and easily absorbs moisture from the air.
It contains dapagliflozin, as propanediol monohydrate, a SGLT-2 inhibitor; and sitagliptin, as phosphate monohydrate, a DPP-4 inhibitor. [1] It is taken by mouth . [ 1 ]
Trisodium phosphate was at one time extensively used in formulations for a variety of consumer-grade soaps and detergents, and the most common use for trisodium phosphate has been in cleaning agents. The pH of a 1% solution is 12 (i.e., very basic), and the solution is sufficiently alkaline to saponify grease and oils.