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  2. Lamivudine/zidovudine - Wikipedia

    en.wikipedia.org/wiki/Lamivudine/zidovudine

    Lamivudine and zidovudine both competitively inhibit and reduce the activity of reverse transcriptase (RT) causing HIV infected cells to decrease the number of viruses in the body. [14] Lamivudine and zidovudine act as nucleoside analogs, which are substrates for the human nucleoside kinases .

  3. Lamivudine - Wikipedia

    en.wikipedia.org/wiki/Lamivudine

    Lamivudine, commonly called 3TC, is an antiretroviral medication used to prevent and treat HIV/AIDS. [1] It is also used to treat chronic hepatitis B when other options are not possible. [1] It is effective against both HIV-1 and HIV-2. [1] It is typically used in combination with other antiretrovirals such as zidovudine, dolutegravir, and ...

  4. Discovery and development of HIV-protease inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    HIV infects T cells that carry the CD4 antigen on their surface. When HIV infects its target cell it requires fusion of the viral and cellular membranes. [12] The first step is the interaction between envelope proteins of the virus (gp120, gp41) and specific host-cell surface receptors (e.g. CD4 receptor) on the target cell.

  5. Protease inhibitor (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Protease_inhibitor...

    Some of the most well known are antiviral drugs widely used to treat HIV/AIDS, hepatitis C and COVID-19. These protease inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease ) and blocking proteolytic cleavage of protein precursors that are necessary for the production of infectious viral particles .

  6. Multiple health agency websites on HIV, contraception taken ...

    www.aol.com/news/multiple-health-agency-websites...

    The CDC's "HIV Risk Reduction Tool," an interactive tool that allowed users to gauge the risk of certain sexual behaviors, has also been erased. For now, the agency appears to have consolidated ...

  7. List of SJS-inducing substances - Wikipedia

    en.wikipedia.org/wiki/List_of_SJS-inducing...

    Lamictal Modafinil [13] Provigil Nevirapine [citation needed] Norfloxacin [14] Oseltamivir [citation needed] Oxicams [7] Ampiroxicam, Piroxicam, Tenoxicam, Droxicam, Lornoxicam, Meloxicam, Isoxicam: Paracetamol [15] [16] Acetaminophen, Panadol, Tylenol Penicillins [5] Phenytoin [5] Rivoraxaban [17] Xarelto: Sitagliptin [citation needed ...

  8. Management of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Management_of_HIV/AIDS

    SARS-CoV-2 and HIV-1 have similarities—notably both are RNA viruses—but there are important differences. As a retrovirus, HIV-1 can insert a copy of its RNA genome into the host's DNA, making total eradication more difficult. [156] The virus is also highly mutable making it a challenge for the adaptive immune system to develop a response.

  9. Lamotrigine - Wikipedia

    en.wikipedia.org/wiki/Lamotrigine

    Lamotrigine, sold under the brand name Lamictal among others, is a medication used to treat epilepsy and stabilize mood in bipolar disorder. [ 5 ] [ 8 ] For epilepsy, this includes focal seizures , tonic-clonic seizures , and seizures in Lennox-Gastaut syndrome . [ 8 ]

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