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This is an accepted version of this page This is the latest accepted revision, reviewed on 26 February 2025. Plant species, recreational drug (kratom) Mitragyna speciosa Conservation status Least Concern (IUCN 3.1) Scientific classification Kingdom: Plantae Clade: Tracheophytes Clade: Angiosperms Clade: Eudicots Clade: Asterids Order: Gentianales Family: Rubiaceae Genus: Mitragyna Species: M ...
Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.
7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
But some estimates put the toll far higher: An analysis by The Washington Post found kratom listed as the leading or partial cause of death in at least 4,100 deaths from 2020 to 2022, and an ...
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Krypton is highly volatile and does not stay in solution in near-surface water, but 81 Kr has been used for dating old (50,000–800,000 years) groundwater. [25] 85 Kr is an inert radioactive noble gas with a half-life of 10.76 years. It is produced by the fission of uranium and plutonium, such as in nuclear bomb testing and nuclear reactors.
(+)-Desmetramadol is a G-protein biased μ-opioid receptor full agonist. [5] It shows comparatively far lower affinity for the δ-and κ-opioid receptors. [6] The two enantiomers of desmetramadol show quite distinct pharmacological profiles; [7] both (+) and (−)-desmetramadol are inactive as serotonin reuptake inhibitors, [8] but (−)-desmetramadol retains activity as a norepinephrine ...