Search results
Results from the WOW.Com Content Network
Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C 5 H 4 N 4 O 3. It forms ions and salts known as urates and acid urates, such as ammonium acid urate. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. [1]
Crystals that can be found in normal urine include uric acid, monosodium urate, triple phosphate (ammonium magnesium phosphate), calcium oxalate, and calcium carbonate. [124] Crystals can also appear as poorly defined aggregates of granular material, termed amorphous urates or amorphous phosphates (urates form in acid urine while phosphates ...
Hypouricemia or hypouricaemia is a level of uric acid in blood serum that is below normal. In humans, the normal range of this blood component has a lower threshold set variously in the range of 2 mg/dL to 4 mg/dL, while the upper threshold is 530 μmol/L (6 mg/dL) for women and 619 μmol/L (7 mg/dL) for men. [1]
The proportions are 78% beta-hydroxybutyric acid, 20% acetoacetic acid and 2% acetone. The test used in the urine test strips is based on the reaction of sodium nitroprusside (nitroferricyanide). In this reaction the acetoacetic acid in an alkali medium reacts with the sodium nitroprusside producing a magenta coloured complex: [ 6 ] [ 14 ]
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [4] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
Fractional excretion of other substances can be measured to determine kidney clearance including urea, uric acid, and lithium. These can be used in patients undergoing diuretic therapy, since diuretics induce a natriuresis. Thus, the urinary sodium concentration and FE Na may be higher in patients receiving diuretics in spite of prerenal ...
Uricosuria refers to uric acid in the urine. Urine levels of uric acid can be described as: Hyperuricosuria, an abnormally high level of uric acid in the urine; Hypouricosuria, an abnormally low level of uric acid in the urine; Agents that increase uric acid in the urine are termed uricosurics
High levels of uric acid often present as a consequence of elevated lactic acid in GSD I patients. When lactate levels are elevated, blood-borne lactic acid competes for the same kidney tubular transport mechanism as urate, limiting the rate which urate can be cleared by the kidneys into the urine.