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The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary ...
α-Melanocyte-stimulating hormone (α-MSH) is an endogenous peptide hormone and neuropeptide of the melanocortin family, with a tridecapeptide structure and the amino acid sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH 2.
The melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a G protein–coupled receptor that binds to a class of pituitary peptide hormones known as the melanocortins, which include adrenocorticotropic hormone (ACTH) and the different forms of melanocyte-stimulating hormone (MSH).
The role of alpha-melanocyte-stimulating hormone (α-MSH) in promoting melanin diffusion has been known since the 1960s. [39] In the 1980s, scientists at University of Arizona began attempting to develop α-MSH and analogs as potential sunless tanning agents, and synthesized and tested several analogs, including afamelanotide , then called ...
The Fischer–Saller scale, named after Eugen Fischer and Karl Saller is used in physical anthropology and medicine to determine the shades of hair color. The scale uses the following designations: A (very light blond), B to E (light blond), F to L (), M to O (dark blond), P to T (light brown to brown), U to Y (dark brown to black) and Roman numerals I to IV and V to VI (red-blond).
The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM).. This list continues the information at List of MeSH codes (D05).
A cat hair showing light and dark bands caused by alternating production of agouti-signaling protein and α-MSH. The agouti gene, the Agouti-signaling protein (ASIP) is responsible for variations in color in many species. Agouti works with extension to regulate the color of melanin which is produced in hairs.
The pars intermedia secretes α-melanocyte-stimulating hormone (α-MSH), and corticotropin-like intermediate peptide. [ citation needed ] It appears to be tonically inhibited by the hypothalamus . In the human fetus , this area produces melanocyte stimulating hormone (MSH) which causes the release of melanin produced in melanocytes that can ...
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