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The fixed-dose combination of pertuzumab, trastuzumab, and hyaluronidase was approved for medical use in the United States in June 2020. [5] [10]The FDA's approval was based on the results of a non-inferiority study in participants with HER2-positive early breast cancer, which demonstrated the fixed-dose combination of pertuzumab, trastuzumab, and hyaluronidase had comparable efficacy and ...
Unlike other types of hair loss — like male pattern baldness that just occurs naturally with age — there’s usually an inciting event or factor that causes telogen effluvium hair loss.
Another type of stress-related hair loss is a hair-pulling disorder known as trichotillomania. It can also be triggered by anxiety and stress, causing some individuals to pull their hair out.
Hair loss is a well-known side effect of many chemotherapy drugs used to treat certain forms of cancer. Similar to other toxins that cause hair loss, hair loss from cancer medications usually isn ...
Trastuzumab is given by slow injection into a vein and injection just under the skin. [30] [33] Common side effects include fever, infection, cough, headache, trouble sleeping, and rash. [30] Other severe side effects include heart failure, allergic reactions, and lung disease. [30] Use during pregnancy may harm the baby. [22]
Finasteride is used to treat male pattern hair loss. [25] Treatment provides about 30% improvement in hair loss after six months of treatment, and effectiveness only persists as long as the drug is taken. [20] There is no good evidence for its use in women. [14] It may cause gynecomastia, erectile dysfunction and depression. [26]
“There's a form of stress-induced hair loss called telogen effluvium, and any stressor on the body, whether it’s pregnancy, surgery, emotional stress, or rapid weight loss, can cause it ...
Pertuzumab is administered as an intravenous infusion in combination with trastuzumab and docetaxel as a first line treatment for HER2-positive metastatic breast cancer. [4] [3] It is also used in the same combination as a neoadjuvant (given to reduce the size of a tumor, prior to surgery or radiation) for HER2-positive early breast cancer; as of 2016 this use had not been shown to increase ...