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If a proposal is still in the early formative stages and it is desired to gather creative suggestions from others on what purpose and direction such a proposal should have, one may wish to temporarily use the {{Brainstorming}} header template, and later use {{Draft proposal}} when these matters are clearer.
The NIAAA functions both as a funding agency that supports research by external research institutions and as a research institution itself, where alcohol research is carried out in‐house. [1] It funds approximately 90% of all such research in the United States. [2] The NIAAA publishes the academic journal Alcohol Research: Current Reviews.
Alcohol abuse during adolescence, especially early adolescence (i.e. before age 15), may lead to long-term changes in the brain which leaves them at increased risk of alcoholism in later years; genetic factors also influence age of onset of alcohol abuse and risk of alcoholism. [86] For example, about 40 percent of those who begin drinking ...
Not only does alcoholism not follow the model of a 'disease,' it is not amenable to standard medical treatment." She says that "Medical doctors' rejection of the disease theory of alcoholism has a strong basis in the biomedical model underpinning most of their training" and that "medical research on alcoholism does not support the disease model."
ABMRF/The Foundation for Alcohol Research is a private, non-profit foundation supporting young investigators researching the effects of alcohol on health and behavior.The Foundation's mission is "To achieve a better understanding of the effects of alcohol on the health and behavior of individuals; To provide the scientific basis for the prevention, treatment and future cure of alcohol-use ...
Alcohol has a powerful effect on glutamate as well. Alcohol decreases glutamate's ability to bind with NMDA and acts as an antagonist of the NMDA receptor, which plays a critical role in LTP by allowing Ca2+ to enter the cell. These inhibitory effects are thought to be responsible for the "memory blanks" that can occur at levels as low as 0.03% ...
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Alcohol tolerance is increased by regular drinking. [1] This reduced sensitivity to the physical effects of alcohol consumption requires that higher quantities of alcohol be consumed in order to achieve the same effects as before tolerance was established. Alcohol tolerance may lead to (or be a sign of) alcohol dependence. [1]