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About 20,000 protein coding genes are expressed in human cells and almost 75% of these genes are expressed in the normal lung. [ 83 ] [ 84 ] A little less than 200 of these genes are more specifically expressed in the lung with less than 20 genes being highly lung specific.
Type I cells are the larger of the two cell types; they are thin, flat epithelial lining cells (membranous pneumocytes), that form the structure of the alveoli. [3] They are squamous (giving more surface area to each cell) and have long cytoplasmic extensions that cover more than 95% of the alveolar surface.
Another important cell type is the pulmonary neuroendocrine cell. These are innervated cells that only make up around 0.5% of the respiratory epithelial cells. [7] The ciliated cells are columnar epithelial cells with specialized ciliary modifications. The ciliated cells make up between 50 and 80 per cent of the epithelium. [8]
The lungs are the largest organs in the lower respiratory tract. The lungs are suspended within the pleural cavity of the thorax. The pleurae are two thin membranes, one cell layer thick, which surround the lungs. The inner (visceral pleura) covers the lungs and the outer (parietal pleura) lines the inner surface of the chest wall. This ...
Superficial anatomy of female and male human body Surface projections of the major organs of the trunk, using the vertebral column and rib cage as main reference points of superficial anatomy Superficial anatomy or surface anatomy is important in human anatomy being the study of anatomical landmarks that can be readily identified from the ...
The mesothelium is composed of an extensive monolayer of specialized cells (mesothelial cells) that line the body's serous cavities and internal organs. The main purpose of these cells is to produce a lubricating fluid that is released between layers, [ 4 ] providing a slippery, non-adhesive, and protective surface to facilitate intracoelomic ...
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Simple squamous epithelium falls under the physiological category of exchange epithelium due to its ability to rapidly transport molecules across the tissue layer. To facilitate this movement, some types of simple squamous epithelium may have pores between cells to allow molecules to move through it, creating a leaky epithelium. [3]