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Extreme levels of consumption can cause alcohol poisoning and death; a concentration in the blood stream of 0.36% will kill half of those affected. [2] [3] [4] Alcohol may also cause death indirectly by asphyxiation, caused from vomiting. Alcohol can greatly exacerbate sleep problems.
c. 2,200 per year (U.S.) [8] Alcohol intoxication, also known in overdose as alcohol poisoning, [1] commonly described as drunkenness or inebriation, [9] is the behavior and physical effects caused by a recent consumption of alcohol. [6][10] In addition to the toxicity of ethanol, the main psychoactive component of alcoholic beverages, other ...
EBAC is the estimated blood alcohol concentration (in g/L) A is the mass of alcohol consumed (g). T is the amount time during which alcohol was present in the blood (usually time since consumption began), in hours. β is the rate at which alcohol is eliminated, averaging around 0.15 g/L/hr. [30]
After binge drinking, unconsciousness can occur and extreme levels of consumption can lead to alcohol poisoning and death (a concentration in the blood stream of 0.40% will kill half of those affected [13] [medical citation needed]). Alcohol may also cause death indirectly, by asphyxiation from vomit.
Competitive inhibition. Ethanol (C. 2H. 5OH) serves as a competitive inhibitor to methanol (CH. 3OH) and ethylene glycol ((CH2OH)2) for the enzyme alcohol dehydrogenase in the liver when present in large amounts. For this reason, ethanol is sometimes used as a means to treat or prevent toxicity following accidental ingestion of these chemicals.
Alcohol-related brain damage[1][2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe, [3] limbic system, and cerebellum, [4] with widespread cerebral ...
Other conditions that may present similarly include other causes of high anion gap metabolic acidosis such as diabetic ketoacidosis, toxic alcohol ingestion, and starvation ketosis. [2] Toxic alcohol ingestion includes methanol and ethylene glycol poisoning. [6] Pancreatitis, alcoholic hepatitis, and gastritis may also result in similar ...
The osmol gap is typically calculated with the following formula (all values in mmol/L): = = ([+] + [] + []) In non-SI laboratory units: Calculated osmolality = 2 x [Na mmol/L] + [glucose mg/dL] / 18 + [BUN mg/dL] / 2.8 + [ethanol/3.7] [3] (note: the values 18 and 2.8 convert mg/dL into mmol/L; the molecular weight of ethanol is 46, but empiric data shows that it does not act as an ideal ...