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Subacute sclerosing panencephalitis (SSPE), also known as Dawson disease, is a rare form of progressive brain inflammation caused by a persistent infection with the measles virus. The condition primarily affects children, teens, and young adults. It has been estimated that about 2 in 10,000 people who get measles will eventually develop SSPE. [1]
The virus causes measles, a highly contagious disease transmitted by respiratory aerosols that triggers a temporary but severe immunosuppression.Symptoms include fever, cough, runny nose, inflamed eyes and a generalized, maculopapular, erythematous rash and a pathognomonic Koplik spot seen on buccal mucosa opposite to lower 1st and 2nd molars.
Pneumonia is the most common fatal complication of measles infection and accounts for 56–86% of measles-related deaths. [89] Possible consequences of measles virus infection include laryngotracheobronchitis, sensorineural hearing loss, [51] and—in about 1 in 10,000 to 1 in 300,000 cases [90] —panencephalitis, which is usually fatal. [91]
Measles is particularly dangerous for children under five years old and babies, and can cause pneumonia or swelling of the brain. Skip to main content. Sign in. Mail. 24/7 Help ...
Roughly a day after the fever sets in come the three C’s of measles: cough, conjunctivitis (pink eye) and coryza (a runny nose). Some kids may be sensitive to light and start to squint, as well.
There are many diseases known to cause ocular or visual changes. Diabetes , for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more.
Two dozen cases of measles have been reported in a small West Texas county that has one of the state’s highest vaccine exemption rates.. In Gaines County, which has a population of about 22,000 ...
While a primary infection can practically be viewed as the root cause of an individual's current health problem, a secondary infection is a sequela or complication of that root cause. For example, an infection due to a burn or penetrating trauma (the root cause) is a secondary infection. Primary pathogens often cause primary infection and often ...