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Grapefruit–drug interactions that affect the pre-systemic metabolism (i.e., the metabolism that occurs before the drug enters the blood) of drugs have a different duration of action than interactions that work by other mechanisms, such as on absorption, discussed below.
"According to the FDA, Seville oranges and tangelos may interact the same way that grapefruit does on certain medications," says Gans. It's also a good idea to read the paperwork that comes with ...
Plus, it’s high in fiber and water, which both fill you up. One whole fruit contains roughly 100 calories and is nearly 90% water by weight. ... While there are many drugs that interact with ...
The pomelo, while not itself toxic, can cause adverse interactions similar to those caused by the grapefruit with a wide range of prescription drugs. These occur by the inhibition of cytochrome P450 -mediated metabolism of prescription drugs including for example some anti-hypertensives , some anticoagulants , some anticancer agents , some anti ...
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
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Grapefruit juice is an inhibitor of CYP3A4. Therefore I think bupropion does NOT interact with grapefruit juice. Reference [1] concluded that multiple doses of bupropion does NOT induce CYP2B6, CYP3A4, and CYP2E1 in human. It doesn't support a major interaction with grapefruit juice. My suggestion would be removing buproprion from the list.
Candied peel: "Like with other citrus fruits, the generous rind of the pomelo can be cooked in a sugar syrup to create candied peel or can be boiled in water with sugar to make a marmalade ...