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Common side effects include gastrointestinal effects such as nausea, vomiting, and diarrhea, as well as headache and insomnia. Postmarketing surveillance has revealed a variety of relatively rare but serious adverse effects associated with all members of the fluoroquinolone antibacterial class.
[3] [36] Levofloxacin may produce fewer of these rare serious adverse effects than other fluoroquinolones. [48] There is some disagreement in the medical literature regarding whether and to what extent levofloxacin and other fluoroquinolones produce serious adverse effects more frequently than other broad spectrum antibacterial drugs. [49] [50 ...
According to Forbes, there have been 45,000 reported cases of side effects related to fluoroquinolones. 23.1 million patients filled prescriptions for oral flouroquinolones in 2011.
Possible side effects [4] Mechanism of action Aminoglycosides; Amikacin: Amikin: Infections caused by Gram-negative bacteria, such as Escherichia coli and Klebsiella particularly Pseudomonas aeruginosa. Effective against aerobic bacteria (not obligate/facultative anaerobes) and tularemia. All aminoglycosides are ineffective when taken orally as ...
[3] [4] Some of the serious adverse effects which occur more commonly with fluoroquinolones than with other antibiotic drug classes include CNS and tendon toxicity. [3] [5] The currently marketed quinolones have safety profiles similar to that of other antimicrobial classes. [3] The serious events may occur with therapeutic or with acute overdose.
Tendinitis and rupture, usually of the Achilles tendon, are class-effects of the fluoroquinolones, most frequently reported with pefloxacin. [6] The estimated risk of tendon damage during pefloxacin therapy has been estimated by the French authorities in 2000 to be 1 case per 23,130 treatment days as compared to ciprofloxacin where it has been estimated to be 1 case per 779,600.
Adverse effects of fluoroquinolones discusses mild side effects aswell. --Doc James (talk · contribs · email) 15:04, 27 February 2009 (UTC) Most drugs can have adverse effects, but fluoroquinolone is the only drug X that has its own Wikipedia article "Adverse effects of X".
[7] [8] A drug may be classified as second-line instead of first-line for one of three possible reasons: 1) it may be less effective than the first-line drugs (e.g., p-aminosalicylic acid), 2) it may have toxic side-effects (e.g., cycloserine), or 3) it may be effective, but unavailable in many developing countries (e.g., fluoroquinolones ...
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